Paul preaches in the synagogue in Pisidian Antioch (Acts 13:14) -- his standard method is synagogue first, then the broader city. His message presents Jesus as fulfillment of the law and prophets.

Winger notes this is a different Antioch (Pisidian Antioch, further north). Paul's pattern in the synagogues is to connect Jesus to the law and prophets -- presenting him as the fulfillment of messianic expectation for a Jewish audience.